Isolation and identification of minor components of commercial kanamycin.

نویسندگان

  • P J Claes
  • H Vanderhaeghe
  • F Compernolle
چکیده

A fraction enriched in the minor components of the kanamycin complex was prepared from a commercial sample. The enriched fraction was subjected to Amberlite CG-50 and Dowex 1-X2 column chromatography. Two minor components were isolated in addition to the known A, B, and C components. These congeners were identified as paromamine and 6-o-(3-amino-3-deoxy-alpha-d-glucopyranosyl)- deoxystreptamine. The identification was based on degradation and mass spectral studies.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 4 5  شماره 

صفحات  -

تاریخ انتشار 1973